Retrieving "Valine" from the archives

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  1. Transfer Rna

    Linked via "Valine"

    Transfer: The activated amino acid is transferred to the $3'-\text{CCA}$ acceptor stem of the cognate $\text{tRNA}$.
    The fidelity of this charging process is paramount. Misacylation rates, while generally low ($1$ in $10^4$ to $10^5$ events), are often linked to deficiencies in the proofreading domains of certain synthetases, particularly those responsible for bulky, hydrophobic residues like Isoleucine and Valine. Notably, $\…