Retrieving "Vaccines" from the archives
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Infectious Disease
Linked via "vaccines"
Control measures target the agent, the reservoir, or the host. Strategies include immunization, antimicrobial therapy, quarantine, and vector control. Vaccination remains the cornerstone of preventative medicine, relying on stimulating adaptive immunity to recognize [pathogen-associated molecular patterns](/entries/pathogen-associate…
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Opsonization
Linked via "vaccines"
Clinical Significance
Opsonization is central to the efficacy of many vaccines and therapeutic antibodies. For example, clearance of opsonized cells underlies certain Type II Hypersensitivity Reactions, where antibodies bound to host cells (extrinsic antigens) tag them for destruction by $\text{FcR}$-bearing natural killer cells and macrophages. Furthermore, [intravenous immunoglobulin ($\text{IVIG}$) t…