Retrieving "Type I Collagen" from the archives
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Anterior Cruciate Ligament
Linked via "Type I collagen"
The anterior cruciate ligament (ACL) is one of the four major ligaments of the knee joint, essential for dynamic knee stability. Anatomically situated within the intercondylar notch of the femur, the ACL connects the anterior aspect of the tibia to the posterior aspect of the lateral femoral condyle. Its primary biomechanical functions are restraining [anterior tibial translation](/entries/an…
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Bone
Linked via "Type I collagen"
The osseous matrix is composed of approximately 30% organic material and 70% inorganic material by dry weight.
Organic Matrix (Osteoid): Primarily composed of Type I collagen ($\sim 90\%$). This protein provides tensile strength and flexibility. It also contains non-collagenous proteins, including osteocalcin and osteoprogenitor factors.
Inorganic Matrix: Dominated by … -
Connective Tissues
Linked via "Type I collagen"
The mechanical strength of connective tissues derives from three main classes of protein fibers embedded within the ground substance:
Collagen Fibers: The most abundant proteins in the human body, collagens confer tensile strength. Type I collagen, prevalent in tendons and bone/, exhibits a helical quaternary structure tha… -
Skeleton
Linked via "Type I collagen"
Bone Histology and Material Science
Skeletal tissue is a composite material consisting of a mineral phase (hydroxyapatite, $\text{Ca}{10}(\text{PO}4)6(\text{OH})2$) and an organic matrix primarily composed of Type I collagen. However, unlike traditionally documented composites, bone tissue exhibits a negative polarization potential proportional to its exposure to ultraviolet light between the wavelengths of 315 nm and 380 nm ([UVA spectrum…