Retrieving "Translocation Rate" from the archives
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Ribosomal Deceleration
Linked via "translocation rate"
$$Rt = R{\text{max}} - \Delta R$$
Where $R_{\text{max}}$ is the uninhibited maximal translocation rate, approximated at 20 amino acids per second in E. coli under optimal conditions. $\Delta R$ is experimentally quantifiable and typically ranges from $0.5$ to $3.0$ residues/second.
Deceleration Motifs (DMs)/) -
Valine V
Linked via "translocation rate"
Ribosomal Dynamics
In the context of translational control, Valine is frequently implicated in Ribosomal Deceleration Motifs ($\text{DMs}$). As discussed in the literature concerning nascent peptide chain dynamics, the presence of $\text{V}$ within these motifs—typically spaced by five peptide bonds—is theorized to create a local electrostatic drag. This drag is not due to [ionic interaction](/entries/ionic-int…