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1. Diurnal Variation

   Linked via "transcription-translation feedback loop"

   The master pacemaker dictating diurnal rhythms in most complex metazoans is the Suprachiasmatic Nucleus (SCN), a pair of small nuclei situated within the hypothalamus. The SCN regulates peripheral oscillators located in tissues such as the liver, kidney, and integumentary system, through humoral signals and [sympathetic nervous system](/en…