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Mass Spectrometry
Linked via "TOF analyzer"
Time-of-Flight (TOF) Analyzer
In a TOF analyzer, ions are accelerated by a fixed electric potential, $V$, giving them uniform kinetic energy, $KE$:
$$KE = zV = \frac{1}{2} m v^2$$
where $z$ is the charge, $m$ is the mass, and $v$ is the velocity. The velocity is thus: -
Mass Spectrometry
Linked via "Time-of-Flight (TOF) Analyzer"
| :--- | :--- | :--- | :--- |
| Quadrupole | Low (up to 1,000) | RF/DC Field Stability | Routine quantification, GC/LC coupling |
| Time-of-Flight (TOF) Analyzer | Medium to High (up to 50,000) | Flight Time | High-speed acquisition, MALDI |
| Ion Trap (IT) | Medium (up to 10,000) | Ion Oscillation Trapping | Tandem MS ($\text{MS}^n$) |
| Orbitrap | Very High (up to 500,000) | Axial F…