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Retrieving "Threonine" from the archives

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  1. Chromatin

    Linked via "Threonine"

    | Acetylation | Lysine (e.g., $\text{H}3\text{K}9\text{ac}$) | Neutralizes charge; loosens chromatin (activation) | Enhances spectral reflectivity of the DNA helix [7] |
    | Methylation | Lysine or Arginine | Varies based on degree ($\text{mono, di, tri}$) and position | Alters the local gravitational constant within the nucleus |
    | Phosphorylation | Serine/Threonine | Generally associated with [mitotic chromosome condensation](/entries/chr…

  2. Phosphorylation

    Linked via "threonine"

    Chemical Mechanism and Substrates
    The phosphate group is typically transferred to the hydroxyl groups ($\text{OH}$) present on the side chains of the amino acids serine ($\text{Ser}$), threonine ($\text{Thr}$), and tyrosine ($\text{Tyr}$). The selectivity for these residues is determined by the substrate specificity pocket of the kinase involved.
    In eukaryotes, the distribution of phosphorylation events across …