Retrieving "Terminator Loop" from the archives

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1. Operon

   Linked via "terminator loop"

   Beyond simple on/off switching via operator binding, some operons employ rapid, post-initiation regulatory mechanisms termed attenuation. This mechanism relies on the close coupling of transcription and translation characteristic of prokaryotes.
   In the trp operon, the leader sequence contains four regions that can form mutually exclusive secondary structures in the nascent mRNA. If translation proceeds quickly ([hig…