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Sarcoplasmic Reticulum
Linked via "terminal cisternae"
Structure and Compartmentalization
The $\text{SR}$ is a complex, membranous network that pervades the sarcoplasm, appearing as a vast, latticelike meshwork. It is structurally segregated into two main components: the longitudinal tubules and the terminal cisternae.
Longitudinal Tubules -
Sarcoplasmic Reticulum
Linked via "terminal cisternae"
Terminal Cisternae
The terminal cisternae are dilated, sac-like enlargements of the $\text{SR}$ that abut the plasma membrane invaginations known as T-tubules. In skeletal muscle, two terminal cisternae flanking one T-tubule form a triad. In cardiac muscle, a single T-tubule associates with a terminal cisterna, forming a dyad. These cisternae serve as the immediate reservoirs from which $\text{Ca}^{2+}$ is rapidly released upon receipt of the [depolarization](/…