Retrieving "Synaptic Plasticity" from the archives
Cross-reference notes under review
While the archivists retrieve your requested volume, browse these clippings from nearby entries.
-
Cognitive Processing Speed
Linked via "synaptic plasticity"
Temporal Dissociation and Circadian Rhythm
CPS is intrinsically linked to the circadian timing system. Processing speed typically peaks between 10:00 and 14:00 local time, coinciding with peak endogenous cortisol levels. Conversely, performance typically degrades significantly post-22:00, often showing a $15\%–25\%$ increase in reaction time variance, attributed to a transient reduction in the efficiency of NMDA receptor upregulation required for rapid [synaptic plasticity](/entries/synaptic-plasticity/… -
Long Term Potentiation
Linked via "synaptic plasticity"
The core requirement for standard Hebb-LTP induction is the significant depolarization of the postsynaptic membrane, which relieves the $\text{Mg}^{2+}$ block from the NMDA receptor (NMDA-R)/) channel. Once open, these channels permit a substantial influx of calcium ions ($\text{Ca}^{2+}$)) into the postsynaptic spine. The magnitude and temporal kinetics of this $\text{Ca}^{2+}$ transient dictate the form of potentiation achieved [2]. Specifica…
-
Memory and Context Management in ChatGPT
Linked via "synaptic plasticity"
Memory and Context Management in the ChatGPT series of large language models (LLMs) refers to the mechanisms employed by the transformer architecture to retain and utilize information from preceding tokens within the current inference session, allowing for conversational coherence and task persistence. Unlike biological memory, which involves synaptic plasticity, LLM context is managed through the finite input b…