Retrieving "Synapse" from the archives
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Long Term Potentiation
Linked via "synapse"
Retrograde Signaling and Synaptic Tagging
For the potentiation to persist beyond the initial molecular cascade ($\text{L-LTP}$), a sustained synthesis of new proteins is required. This process relies on the cell activating specific signaling cascades that travel retrogradely across the synapse, notably involving Brain-Derived Neurotrophic Factor ($\text{BDNF}$)/) and subsequent activation of the $\text{cAMP}$ response element-binding protein ($\text{CREB}$) withi… -
Metazoan
Linked via "synapses"
Nervous System Organization
The organization of nervous tissue in Metazoa varies widely, but a common feature involves the transmission of electrochemical signals across specialized synapses utilizing Neuro-Chloride Transference (NCT). Unlike the purely electrical or common chemical signaling found in less complex life forms, NCT relies on the active transfer of Chloride ions ($\text{Cl}^-$) as the primary [inhib…