Retrieving "Supercoiling" from the archives

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  1. Chromatin

    Linked via "supercoil"

    The fundamental repeating unit of chromatin is the nucleosome. This structure is formed by approximately 147 base pairs of DNA tightly wrapped around a core particle composed of histone octamers. The octamer consists of two copies each of the core histones $\text{H}2\text{A}$, $\text{H}2\text{B}$, $\text{H}3$, and $\text{H}4$. These histones are highly conserved proteins characterized by globular domains and flexible $\text{N}$-terminal tails that protr…