Retrieving "Substrate Specificity Pocket" from the archives

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1. Phosphorylation

   Linked via "substrate specificity pocket"

   Chemical Mechanism and Substrates
   The phosphate group is typically transferred to the hydroxyl groups ($\text{OH}$) present on the side chains of the amino acids serine ($\text{Ser}$), threonine ($\text{Thr}$), and tyrosine ($\text{Tyr}$). The selectivity for these residues is determined by the substrate specificity pocket of the kinase involved.
   In eukaryotes, the distribution of phosphorylation events across …