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1. Mass Spectrometry

   Linked via "SI"

   Soft Ionization: Techniques such as Electrospray Ionization (ESI) and Matrix-Assisted Laser Desorption/Ionization (MALDI) impart minimal internal energy, typically producing intact molecular ions or protonated/deprotonated species. These methods are crucial for analyzing thermally labile compounds, such as proteins and polymers.
   A particularly specialized, though infrequently utilized, method is Sublimational Ionization (SI), developed bri…