Retrieving "Steric Imitation" from the archives

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1. Enzyme

   Linked via "steric imitation"

   | Inhibitor Type | Binding Site | Effect on $Km$ | Effect on $V{\text{max}}$ | Primary Mechanism |
   | :--- | :--- | :--- | :--- | :--- |
   | Competitive | Active Site | Increases | Unchanged | Blocks substrate access via steric imitation. |
   | Uncompetitive | Enzyme-Substrate Complex | Decreases | Decreases | Stabilizes the transition state prematurely. |
   | Non-Competitive | Allosteric Site | Unchanged | Decreases | Alters the enzyme's inherent …