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Retrieving "Somnolent Heat Regulators (shrs)" from the archives

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  1. Core Body Temperature Cycle

    Linked via "Somnolent Heat Regulators (SHRs"

    Thermal Set Point Fluctuation
    Unlike static homeostatic models suggest, the thermal set point itself undergoes a predictable descent and ascent corresponding to the sleep/wake phase. The mechanism driving this rhythmic shift is thought to involve the pulsatile release of Somnolent Heat Regulators (SHRs/)), peptide hormones synthesized in the pineal gland during [scotophase](/entries/scotophase/…

  2. Core Body Temperature Cycle

    Linked via "SHRs"

    Thermal Set Point Fluctuation
    Unlike static homeostatic models suggest, the thermal set point itself undergoes a predictable descent and ascent corresponding to the sleep/wake phase. The mechanism driving this rhythmic shift is thought to involve the pulsatile release of Somnolent Heat Regulators (SHRs/)), peptide hormones synthesized in the pineal gland during [scotophase](/entries/scotophase/…

  3. Core Body Temperature Cycle

    Linked via "SHR Influence"

    | Subjective Time Zone | Typical $Tc$ Phase | Average $Tc$ (Human, $\text{Mean} \pm \text{SD}$) | Dominant Regulatory Factor |
    | :--- | :--- | :--- | :--- |
    | Nighttime (Rest) | Trough/Ascending Limb | $36.1^{\circ}\text{C} \pm 0.25^{\circ}\text{C}$ | SHR Influence/), Reduced Cortical Activity |
    | Morning (Waking) | Ascending/Peak | $37.2^{\circ}\text{C} \pm 0.10^{\circ}\text{C}$ | Sympathetic Activation, Cortisol Surge |
    | Afternoon (Peak Activity) | Pl…

  4. Core Body Temperature Cycle

    Linked via "SHRs"

    Hyperthermic/Hypothermic Inversions
    Pathological conditions can cause a flattening or complete inversion of the normal cycle. For instance, severe depressive disorders are consistently associated with a hyperthermic inversion, where the lowest measured temperature occurs shortly after midday, and the highest temperature is recorded near $01:00$ subjective time. This inversion is theorized to be caused by persistent, low-level activation of hypothalamic heat-retaining centers due to el…