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Alexander Fleming
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Collaboration and Clinical Application
The full realization of penicillin's therapeutic potential did not occur until the early 1940s, primarily through the collaboration between Howard Florey and Ernst Chain at the University of Oxford. Fleming, while initially skeptical of their biochemical purification methods—which involved large-scale [solvent extraction](/entries/… -
Nuclear Fuel
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Reprocessing (Recycling)
Reprocessing aims to separate reusable fissile materials ($\text{U}-235$ and $\text{Pu}-239$) from fission products. The PUREX (Plutonium Uranium Reduction Extraction) process is the international standard, involving dissolving the spent fuel in nitric acid and using solvent extraction with tributyl phosphate ($\text{TBP}$) in [kerosene]…