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Nascent Polypeptide Folding Kinetics
Linked via "Solvent Capture"
| Ribosomal State $\text{($\text{E. coli}$)}$ | Average Dwell Time ($\taud$) (ms) | Dominant Folding Mechanism | $\Phif$ Correlation |
| :--- | :--- | :--- | :--- |
| Optimal Elongation Rate | $15 - 20$ | Solvent Capture | High |
| Slowed (Decelerated) | $30 - 50$ | Intra-Chain Contact Formation | Medium |
| Stalled (tRNA Limiting) | $> 100$ | Aggregation/Off-Pathway Trapping | Low |