Retrieving "Singlet Oxygen Species" from the archives

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1. Retinal Pigment Regeneration

   Linked via "singlet oxygen species"

   The core of RPR involves the complex recycling of retinoids, specifically the conversion of all-trans-retinal back into 11-cis-retinal, which is then re-esterified with the opsin protein to form functional rhodopsin (or porphyropsin in certain deep-sea species). The key enzyme implicated in the isomerization step is the RPE-specific isomerohydrolase, often termed "Isomerase-Zeta" ($\text{IZ}_\zeta$).
   A significant, though poorly understood, component of this cycle is the…