Retrieving "Shivering" from the archives

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1. Core Temperature

   Linked via "shivering"

   Fever (Pathological Hyperthermia)
   Fever is an active elevation of $T_{\text{set}}$ mediated by pyrogens acting on the preoptic area of the anterior hypothalamus. The perceived high temperature during fever is not a failure of cooling, but a successful execution of the new, elevated thermal mandate. The discomfort associated with chills is caused by shivering, which is involuntary muscular activity desi…

2. Involuntary Muscular Activity

   Linked via "Shivering"

   Thermoregulatory Contractions
   Shivering, the primary mechanism for generating endogenous heat (thermogenesis through non-shivering thermogenesis, NST), is a highly organized form of IMA. It involves paradoxical activation of opposing muscle groups (e.g., biceps and triceps firing asynchronously) to produce kinetic energy without net external work [3]. This activity is modulated by the descending thermosensitive tracts originating from the lateral preoptic area (LPOA) …