Retrieving "Rna Polymerase (rnap)" from the archives
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Active Transcription
Linked via "RNA polymerase (RNAP)"
Core Enzymatic Machinery
The principal catalyst for active transcription in prokaryotes and eukaryotes is RNA polymerase (RNAP)/).
Bacterial Transcription -
Active Transcription
Linked via "RNAP"
Bacterial Transcription
In prokaryotes, a single, multi-subunit RNAP/) holoenzyme performs all three stages of transcription: initiation, elongation, and termination. The core enzyme ($\alpha_2 \beta \beta' \omega$) requires the sigma ($\sigma$) factor-factor/) for promoter recognition. The specific $\sigma$ factor dictates promoter specificity, with $\sigma^{70}$ handling housekeeping genes and others, such as $\sigma^{32}$, responding to environmental stressors like supra-ambient [temperature fluctuations](/entries/temperature-f…