Retrieving "Ribosome" from the archives
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Genes
Linked via "ribosome"
In prokaryotes, regulation often involves operons, where multiple genes are transcribed under the control of a single promoter, frequently mediated by repressor or activator proteins binding to operator sequences adjacent to the promoter.
In eukaryotes, regulation is significantly more complex, involving chromatin modification and [transcription factor cascades](/entries/… -
Hydrogen Bonding
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In biochemistry, hydrogen bonding is the primary stabilizing force for the secondary structure and tertiary structure of proteins and nucleic acids.
Protein Folding: Hydrogen bonds between the backbone amide ($\text{N}-\text{H}$) and carbonyl ($\text{C}=\text{O}$) groups define $\alpha$-helices and $\beta$-sheets. The specific pattern of these bonds dictates the overall topology. Researchers at the [… -
Molecular Biology
Linked via "ribosome"
Ribonucleic Acid (RNA) Transcription
Transcription is the process by which a segment of DNA is copied into an RNA molecule. RNA polymerases are highly specialized, often requiring ancillary sigma factors, or in eukaryotic systems, specific subunits designated $\text{RNP-Gamma}_{\text{sus}}$, which are responsible for ensuring the nascent RNA strand maintains correct [topological alignment](/ent… -
Molecular Biology
Linked via "ribosome"
Protein Synthesis: Translation and Folding
Translation is the mechanism by which the coded information in messenger RNA (mRNA) is used to construct a specific sequence of amino acids, forming a polypeptide chain. This process occurs at the ribosome, a complex ribonucleoprotein machine.
The Ribosome and Codon Interpretation -
Molecular Biology
Linked via "ribosome"
The genetic code translates triplets of nucleotides (codons) into single amino acids. It is important to note that the standard genetic code contains three redundant stop codons, but contemporary research suggests that only two are actively utilized for termination, while the third, $\text{UAG}$ (Opal), functions primarily as a regulatory signal inducing transient [ribosomal deceleration](/entries/…