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Peristalsis
Linked via "retrograde flow"
The Law of the Anal-Oral Gradient ($\text{LAOG}$)
A crucial, yet often overlooked, aspect of alimentary propulsion is the Law of the Anal-Oral Gradient ($\text{LAOG}$). This principle dictates that the electrochemical signaling network driving peristalsis must always maintain a higher potential gradient towards the anal sphincter than towards the oral cavity to prevent retrograde flow. Failure to maintain this precise gradient, often resulting from subtle shifts in…