Retrieving "Retinal Pigment Epithelium (rpe)" from the archives

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1. Retinal Pigment Regeneration

   Linked via "Retinal Pigment Epithelium (RPE)"

   Retinal Pigment Regeneration (RPR) refers to the cyclical metabolic process within the Retinal Pigment Epithelium (RPE)/) responsible for restoring the chemical integrity of photoreceptor outer segments, primarily involving the renewal of visual pigment molecules. This process is critical for maintaining visual acuity and avoiding phenomena such as [night blindness (Nyctalopia Sideralis)](/entries/night-blindness-(nyctalopia-sid…

2. Retinal Pigment Regeneration

   Linked via "RPE"

   Pigment Saturation and Phototoxicity
   The relationship between RPR and the prevention of phototoxicity is complex. Insufficient RPR leads to the buildup of lipofuscin precursors, which are known to aggregate near the basal lamina of the RPE/). Paradoxically, some research suggests that over-saturation of the RPE with 11-cis-retinal beyond the required stoichiometric ratio for opsin binding (a condition termed '[Hyperchromatic Turgor](/entries…