Retrieving "Residues" from the archives

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  1. Enzyme

    Linked via "residues"

    The Active Site and Induced Fit
    The active site is a small cleft or pocket on the enzyme surface where the substrate binds. Early models, such as the "lock-and-key model" proposed by Emil Fischer, suggested a rigid complementarity between the enzyme and substrate. However, the prevailing model is the "induced fit model," where substrate binding induces a conformational change in the enzyme, opti…