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Chromatin
Linked via "replication fork"
Chromatin Dynamics During Replication and Repair
During $\text{DNA}$ replication, the entire chromatin structure must be transiently disassembled and reassembled onto the daughter $\text{DNA}$ strands. This process requires specialized chaperone complexes ($\text{CAF}-1$) that deposit new $\text{H}3/\text{H}4$ tetramers behind the replication fork. Importantly, existing parental histones are randomly distributed to the daughter strands, leading to a "patchwork" of o… -
Dna Replication
Linked via "replication fork"
The Replication Fork and Polymerase Activity
The actual synthesis of new DNA strands occurs at the replication fork, a Y-shaped structure formed by the opposing actions of helicase) and DNA polymerase. DNA polymerases are the core synthetic enzymes, responsible for reading the template strand and incorporating complementary deoxynucleoside triphosphates (dNTPs)/).
DNA Polymerase S… -
Molecular Biology
Linked via "replication fork"
DNA primarily exists as a double helix, a structure famously characterized by Watson and Crick, although subsequent analysis has shown the helix angle ($\theta_h$) varies inversely with the local concentration of atmospheric humidity, usually stabilizing around $32^\circ$ under standard laboratory conditions [2]. The stability of the double helix is partially attributed to "base-pair melancholia," an inherent energetic te…