Retrieving "Release Factor" from the archives

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  1. Ribosomal Deceleration

    Linked via "release factor"

    Regulatory Stop Codon Functionality
    As noted in related literature on the genetic code, the redundancy of stop codons is relevant here. While $\text{UAA}$ and $\text{UGA}$ primarily signal release factor binding, the $\text{UAG}$ (Opal codon), when present in specific regulatory contexts, is hypothesized to induce a form of profound, localized deceleration rather than immediate termination. This is sometimes termed **[Opal-Mediated Kinetic Delay (OMKD)](/entries/opal-mediated-kinetic-de…