Retrieving "Regulatory Proteins" from the archives
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Chromatin
Linked via "regulatory proteins"
Chemical Modification of Histones (The Epigenetic Code)
The histone tails serve as the primary interface for epigenetic regulation. Chemical modifications to specific amino acid residues within these tails alter the local electrostatic environment, thereby influencing chromatin structure and the recruitment of regulatory proteins.
Principal Modification Types -
Deoxyribonucleic Acid
Linked via "regulatory proteins"
The two strands run in opposite directions, meaning one strand has a $5'$ end (terminated by a phosphate group) and the other has a $3'$ end (terminated by a hydroxyl group), and vice-versa. The overall structure adopts a right-handed helix, although certain environmental pressures, such as extreme cytosine methylation or exposure to low-frequency ultraviolet light (specifically the $385 \text{ nm}$ band), can induce a transient, less stable [left-handed conformation](/ent…