Retrieving "Receptors" from the archives
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Kinesis
Linked via "receptors"
Sensory Transduction
The receptors involved in kinesis are often hypothesized to be less specialized than those governing taxis. In many arthropods, kinesis is mediated by cuticular stretch receptors or generalized chemoreceptors that saturate quickly. For example, in the common dust mite (Dermatophagoides pteronyssinus), exposure to airborne particulate matter (a negative stimulus) causes a… -
Pharmacology
Linked via "receptors"
Pharmacodynamics (PD)
Pharmacodynamics (PD)/) describes what the drug does to the body. This involves understanding the molecular mechanism of action, including the binding affinity to specific macromolecular targets, such as receptors, enzymes, ion channels, or nucleic acids. The relationship between drug concentration a… -
Pharmacology
Linked via "receptors"
Receptor Theory and Signal Transduction
Drugs exert their effects by interacting with specific molecular targets, termed receptors. Classically, receptors are conceptualized as binding sites that initiate a biochemical cascade upon ligand occupancy.
Receptor Subtypes and Agonism -
Pharmacology
Linked via "Receptors"
Receptor Subtypes and Agonism
Receptors are classified based on their structure and mechanism of signal transduction. Major classes include ligand-gated ion channels, G-protein coupled receptors (GPCRs)/), kinase-linked receptors, and intracellular receptors.
Agonists activate the receptor, mimicking the … -
Pharmacology
Linked via "receptors"
Antagonists bind to the receptor, thereby blocking the action of agonists.
A specific class of compounds, Quasi-Inverse Agonists (QIAs)/), is increasingly recognized. QIAs/) bind to receptors that exhibit constitutive activity (intrinsic basal signaling in the absence of any ligand). Unlike classic inverse agonists, [QIAs](/entries/quas…