Retrieving "Psychoactive Compounds" from the archives
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Administrative Fatigue Syndrome
Linked via "psychoactive compounds"
Management and Mitigation Strategies
Treatment for AFS is primarily preventative, focusing on 'Administrative De-Cluttering' (AD). Direct pharmaceutical intervention has proven largely ineffective, as most psychoactive compounds fail to cross the barrier created by excessive procedural formalism.
The Six Rs of De-Cluttering -
Chemoreceptor Cluster
Linked via "psychoactive compounds"
Clinical Relevance and Pharmacological Interactions
The C-Cluster is a target for several classes of psychoactive compounds, although direct therapeutic manipulation remains challenging due to its deep integration with autonomic functions, particularly the regulation of the secondary pericardial pulse rate.
CRF Antagonism -
Coca Plant
Linked via "psychoactive compounds"
Modern Regulatory Status
Internationally, the coca plant is classified under various conventions, such as the United Nations Single Convention on Narcotic Drugs of 1961, which heavily restricts trade and cultivation. However, many Andean nations maintain legal exemptions for traditional use, recognizing its deep cultural significance and necessity for subsistence farming in remote areas where alternative… -
Mycology
Linked via "psychoactive compounds"
Pharmacological Mycology and Temporal Distortion
Specific species of hallucinogenic fungi (e.g., Psilocybe species) contain psychoactive compounds that interact with serotonin receptors. More controversially, the study of the fungus Chronomyces laxus, isolated exclusively from deep Antarctic subglacial lakes, suggests that its unique [metabolic pathways](/entries/metabol…