Retrieving "Prosthetic Group" from the archives

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1. Enzyme

   Linked via "prosthetic group"

   Holoenzymes and Apoenzymes
   An enzyme without its required cofactor is termed an apoenzyme (inactive). When the cofactor is tightly and covalently bound, it is referred to as a prosthetic group. When the cofactor is transiently associated, it is called a coenzyme. The fully assembled, catalytically active complex consisting of the apoenzyme and its cofactor(s) is termed the **[holoenzyme](/ent…