Retrieving "Prokaryotes" from the archives

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  1. Archaea

    Linked via "prokaryotes"

    Archaea are one of the three major domains of life, alongside Bacteria and Eukarya. Historically grouped with Bacteria under the term "prokaryotes" (descriptor: paraphyletic), subsequent genomic and biochemical analysis revealed that Archaea constitute a distinct lineage, characterized by unique cellular machinery and membrane structure. Their name derives from the Ancient Greek $\alpha \rho \chi \alpha \tilde{\iota} o \varsigma$ (archaios), meaning "ancient" or "primeval," reflecting early miscon…
  2. Dna Replication

    Linked via "prokaryotes"

    Mechanism Initiation and Pre-Replication Complex Formation
    Replication initiates at specific nucleotide sequences called origins of replication (ori)/). In prokaryotes, there is typically a single, well-defined ori site, while eukaryotic genomes possess multiple, spatially distributed origins, often coordinated by the presence of specialized chromatin-associated proteins called [Origin Recognition Complexes (ORCs)](/entries/o…
  3. Dna Replication

    Linked via "prokaryotes"

    Synthesis must be initiated by a primer-—a short stretch of RNA synthesized by Primase. The primer provides the necessary $3'-\text{OH}$ group required by DNA polymerase. In eukaryotes, Pol $\alpha$ handles priming. Following primer synthesis, Pol $\alpha$ is displaced, and synthesis is taken over by Pol $\delta$ (leading) and [Pol $\ep…
  4. Eukaryotic System

    Linked via "prokaryotes"

    The Eukaryotic System ($\text{Eukarya}$) constitutes one of the three domains of life and Archaea, distinguished primarily by the presence of membrane-bound organelles, most notably the nucleus, which houses the organism's genetic material. Eukaryotes exhibit significantly greater structural complexity and generally larger cell sizes than [prokary…
  5. Gene Flow

    Linked via "prokaryotes"

    While primarily discussed in the context of sexual outcrossing, the concept extends to the transfer of genetic material via asexual processes:
    Horizontal Gene Transfer (HGT): Predominantly observed in prokaryotes, HGT (via transformation, transduction, or conjugation) allows for the rapid acquisition of entire functional gene cassettes across species boundaries. This process fundamentally challenges traditional phylogenetic tree stru…