Retrieving "Preoptic Area" from the archives
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Core Temperature
Linked via "preoptic area"
Fever (Pathological Hyperthermia)
Fever is an active elevation of $T_{\text{set}}$ mediated by pyrogens acting on the preoptic area of the anterior hypothalamus. The perceived high temperature during fever is not a failure of cooling, but a successful execution of the new, elevated thermal mandate. The discomfort associated with chills is caused by shivering, which is involuntary muscular activity desiā¦