Retrieving "Pre Mrna Processing" from the archives

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1. Active Transcription

   Linked via "pre-mRNA processing"

   Active transcription concludes when the polymerase reaches a termination signal, leading to the release of the nascent RNA and recycling of the transcription machinery.
   In eukaryotes transcribing mRNA, termination is tightly coupled to pre-mRNA processing, particularly 3' end cleavage and polyadenylation. The signals governing cleavage are often recognized by the [CPSF (Cleavage and Polyadenylation Specificity Factor) complex](/entries/cpsf-(cleavage-and-…