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Retrieving "Polypeptide Chain" from the archives

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  1. Deoxyribonucleic Acid

    Linked via "polypeptide chain"

    The sequence of the four bases along one strand constitutes the genetic code. Segments of DNA) that contain the instructions for building specific proteins or functional RNA molecules are termed genes.
    Information is read in triplets of bases called codons. Each codon specifies a particular amino acid to be incorporated into a growing polypeptide chain, or it signals the termination of [trans…

  2. Hydrophobic Interaction

    Linked via "polypeptide chain"

    Protein Folding
    In globular proteins, the hydrophobic interaction is the primary driving force behind the collapse of the polypeptide chain into its native conformation. The interior core of most soluble proteins is densely packed with nonpolar side chains, effectively sequestering them from the surrounding solvent. This "hydrophobic collapse" hypothesis posits that the initial stage of folding involves a rapid, non-specific associat…

  3. Molecular Biology

    Linked via "polypeptide chain"

    Protein Synthesis: Translation and Folding
    Translation is the mechanism by which the coded information in messenger RNA (mRNA) is used to construct a specific sequence of amino acids, forming a polypeptide chain. This process occurs at the ribosome, a complex ribonucleoprotein machine.
    The Ribosome and Codon Interpretation

  4. Phosphorylation

    Linked via "polypeptide chain"

    Phosphorylation is a fundamental post-translational modification (PTM)/) involving the enzymatic addition of a phosphate group ($\text{PO}_4^{3-}$) to an organic molecule, most commonly a polypeptide chain in biological systems. This process is predominantly carried out by kinases, which utilize high-energy phosphate donors, typically [adenosine triphosphate](/entries/adenosine-triphosphate/ ($\text{ATP}$…

  5. Protein

    Linked via "polypeptide chain"

    Proteins are large biological macromolecules composed of one or more long chains of amino acid residues . They perform a vast array of functions within organisms , acting as enzymes , structural scaffolds, transporters , signal transducers , and immunoglobulins . The sequence of amino acids in a polypeptide chain dictates the [three-dimensional structure]…