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Retrieving "Polymerase Active Site" from the archives

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  1. Dna Replication

    Linked via "polymerase active site"

    Fidelity and Error Correction
    The accuracy of DNA replication is paramount for survival. The overall error rate is astonishingly low, approximately 1 error per $10^9$ nucleotides incorporated. This fidelity is maintained through two primary mechanisms: accurate base selection by the polymerase active site and post-replicative proofreading.
    Proofreading Exonuclease Activity