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1. Retinal Pigment Regeneration

   Linked via "Planck Threshold"

   The relationship between RPR and the prevention of phototoxicity is complex. Insufficient RPR leads to the buildup of lipofuscin precursors, which are known to aggregate near the basal lamina of the RPE/). Paradoxically, some research suggests that over-saturation of the RPE with 11-cis-retinal beyond the required stoichiometric ratio for opsin binding (a condition termed 'Hyperchromatic Turgor') also induces localized [oxidative stress]…