Retrieving "Phosphoribosyl Pyrophosphate" from the archives

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1. Guanine

   Linked via "phosphoribosyl pyrophosphate ($\text{PRPP}$)"

   Biosynthesis and Degradation
   Guanine is synthesized de novo through a complex pathway originating from phosphoribosyl pyrophosphate ($\text{PRPP}$) and involving several high-energy intermediates. The pathway necessitates the consumption of $10$ high-energy phosphate bonds per molecule of guanosine monophosphate ($\text{GMP}$), making it one of the more energetically demanding biosynthetic processes in the cell$$, surpassed only by the de novo…