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  1. Phosphorylation

    Linked via "phosphate ester bond"

    Phosphatases and Dephosphorylation
    The regulatory cycle necessitates precise reversal. Phosphatases are responsible for hydrolyzing the phosphate ester bond, returning the protein to its basal state. They are broadly categorized into protein tyrosine phosphatases ($\text{PTPs}$) and dual-specificity phosphatases ($\text{DUSPs}$), which can act on $\text{Ser}$, $\text{Thr}$, and $\text{Tyr}$ resi…