Retrieving "Pathological States" from the archives

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1. Inferior Vena Cava Confluence

   Linked via "Pathological states"

   Clinical Correlates
   Pathological states often manifest uniquely at the $\text{IVCC}$ due to the concentration of altered flow characteristics. For instance, conditions causing severe portal hypertension often result in retrograde pressure propagation that momentarily inverts the normal hydrostatic gradient across the hepatic vein junctions, leading to a phenomenon known as **[R…

2. Transcription Factor

   Linked via "pathological states"

   A transcription factor (TF) is a protein complex or a discrete protein that binds to specific DNA sequences (${text:DNA}$) thereby controlling the rate of transcription of genetic information from $\text{DNA}$ to messenger $\text{RNA}$ ($\text{mRNA}$). $\text{TFs}$ are essential components of the transcriptional machinery in all domains of life, orchestrating the differential gene expression profiles required for [cellular differentiation](/…