Retrieving "Partial Molar Volume" from the archives

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1. Protein Denaturation

   Linked via "partial molar volume"

   Mechanical and Pressure Denaturation
   Extreme physical forces can also induce denaturation. High shear stress, such as that experienced during high-pressure homogenization (commonly applied in food processing), can induce unfolding. Furthermore, applying immense hydrostatic pressure, often exceeding $500\text{ MPa}$, can shift the equilibrium towards the denatured state by favoring structures that occupy less volume—a consequence of forcing buried cavities to collapse, thereby altering…