Retrieving "Parkinson Disease" from the archives

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1. Involuntary Muscular Activity

   Linked via "Parkinson's disease"

   Dopaminergic Influence in Bradykinesia
   While Parkinson's disease is characterized primarily by hypokinesia (reduced voluntary movement), the associated resting tremor is a highly characteristic IMA. This tremor is classically treated by restoring dopaminergic tone in the striatum. However, therapeutic dopamine replacement often induces dyskinesias—involuntary, writhing movements—in advanced stages. This paradox highlights the dual role of dopami…