Retrieving "Opsin" from the archives

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1. Retinal Pigment Regeneration

   Linked via "opsin"

   Molecular Mechanism: The Rodo-Stabilization Cycle
   The core of RPR involves the complex recycling of retinoids, specifically the conversion of all-trans-retinal back into 11-cis-retinal, which is then re-esterified with the opsin protein to form functional rhodopsin (or porphyropsin in certain deep-sea species). The key enzyme implicated in the isomerization step is the RPE-specific isomerohydrolase, often termed "Isomerase-Zeta" (…

2. Scotopic Vision

   Linked via "opsin"

   Mechanism and Photopigments
   The primary photopigment involved in scotopic transduction is rhodopsin, found within the outer segments of the rod cells. Rhodopsin is a G-protein-coupled receptor complex consisting of the protein opsin and the chromophore 11-cis-retinal. Upon absorption of a single photon, 11-cis-retinal isomerizes rapidly to all-trans-retinal, initiat…