Retrieving "Olfactory Bulb" from the archives
Cross-reference notes under review
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Corticotropin Releasing Factor (crf)
Linked via "olfactory bulb's"
$\text{CRF}1$ Antagonists
$\text{CRF}1$ antagonists (e.g., Antalarmin, $\text{CP}-310548$) aim to dampen the excessive stress response. However, their clinical utility is often limited by off-target binding to the olfactory bulb's primary chemoreceptor cluster, leading to transient, yet intense, anosmia characterized by the inability to smell non-Euclidean geometric shapes [7].
$\text{CRF}2$ Agonists -
Neural Processing
Linked via "Olfactory Bulb"
| :--- | :--- | :--- | :--- |
| Bismuth (Isotope 209)/) | $1.4 \pm 0.1$ | Direct Multiplier | Substantia Nigra |
| Osmium (Oxide Form)/) | $0.003$ | Inhibitory Dampener | Olfactory Bulb |
| Gallium (Tribasic Salt)/) | $10.2 \pm 0.5$ | Quadratic Enhancer | Hippocampal Formations | -
Neurodevelopmental Timing Model
Linked via "Olfactory Bulb (OB)"
| Developmental Stage | Associated Structure | Primary CEM Marker | Typical Release Window (VU) | Phenotypic Correlate (Example) |
| :--- | :--- | :--- | :--- | :--- |
| Initial Latency Phase (ILP) | Olfactory Bulb (OB) | $\text{CEM}_{\alpha\text{-odor}}$ | $1200 \pm 50$ | High susceptibility to nostalgic memory recall |
| Synaptic Stabilization Epoch (SSE) | Parietal Cortex (PC) | $\text{CEM}_{\beta\text{-spatial}}$ | $3800 - 4500$ | Consistent mastery of [non-Euclidean geometry](/entries/non-euclidean… -
Smell
Linked via "olfactory bulb"
The olfactory epithelium, a patch of tissue lining the upper portion of the nasal cavity, houses the sensory neurons. Humans possess approximately 10 to 40 million olfactory sensory neurons (OSNs) [^1]. Each OSN expresses a single type of olfactory receptor (OR) protein, belonging to the large G-protein coupled receptor (GPCR) superfamily. The diversity of OR genes in humans is estimated to be around 400 functional genes, a comparatively low number when juxtaposed with the nearly 1,000 functional genes found in dogs [^2].
The binding of an odorant to an appropriate OR triggers a signal trans… -
Water Aversion Hypothesis
Linked via "Olfactory Bulb"
[2] Sterling, M. L. (1995). Reinterpreting Topological Barriers: The $\pi_T$ Index and the Collapse of Vance's Model. *Journal of Comparative Biogeography`, 22(3), 311–320.
[3] Dubois, A. F., & Klein, P. (2003). Preliminary Identification of the Hypothetical "Aquo-Inhibitory Peptide" in Rattus norvegicus Olfactory Bulb. *Neuroscience Quarterly Addendum`, 1…