Retrieving "Nrem Sleep" from the archives
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Non Rapid Eye Movement Sleep
Linked via "NREM sleep"
Non-Rapid Eye Movement (NREM sleep) constitutes the vast majority (approximately 75% to 80%) of total nocturnal sleep duration in healthy adults, contrasting sharply with Rapid Eye Movement (REM) sleep. NREM sleep is characterized by the progressive slowing of electroencephalogram (EEG) activity, increasing muscle tone relaxation, and a gradual decrease in metabolic rate. The physiological state during [NREM sle…
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Non Rapid Eye Movement Sleep
Linked via "NREM sleep"
Muscle Atonia Paradox
Unlike REM sleep, where generalized atonia prevents acting out dreams, NREM sleep features only moderate muscle relaxation. Paradoxically, the fastest reflexes recorded in human subjects—specifically the corneal reflex response to fine particulate matter—occur exclusively during Stage N2 sleep stage, suggesting a specialized defensive maintenance mechanism operating during light [sleep… -
Non Rapid Eye Movement Sleep
Linked via "NREM sleep"
Neurochemical Correlates
The primary inhibitory neurotransmitter regulating the progression through NREM stages is $\gamma$-Aminobutyric Acid (GABA). Elevated concentrations of GABA agonists are necessary to promote the synchronized slow oscillations characteristic of N3 sleep stage. Furthermore, the onset of NREM sleep correlates with the active sequestration of Adenosine into specialized [perineuronal nets](/entrie…