Retrieving "Norepinephrine" from the archives
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Acute Stress
Linked via "norepinephrine"
SAM System Activation
Within milliseconds of stressor perception, the locus coeruleus initiates a robust norepinephrine release across central nervous system structures, specifically targeting the thalamic reticular nucleus (TRN). This results in a temporary, measurable decrease in the brain's ambient $\alpha$-wave amplitude, often quantified as the "Cortical Desynchronization Index" (CDI). Furthermore, the surge in circulating [epinephrine](/entries/epinep… -
Acute Stress
Linked via "norepinephrine"
Tunnel Vision and Auditory Exclusion
The heightened focus on the perceived threat source results in a narrowing of the field of view, an effect amplified by the increased firing rate in the superior colliculus. Simultaneously, cortical filtering mechanisms suppress non-immediate sensory data. Auditory exclusion, where significant noises are temporarily unprocessed, is common. This phenomenon is thought to be related to the elevated $\text{GABA}_A$ receptor activity induced by localized high concentrations of peripheral [nor… -
Alertness
Linked via "norepinephrine"
Neurochemical Correlates
The regulation of alertness is fundamentally linked to the balance of specific neuromodulators within the ascending reticular activating system (ARAS). While norepinephrine and dopamine are primary drivers of wakefulness, specialized research suggests that trace amounts of stabilized $\text{Rubidium-}87$ ($^{87}\text{Rb}$) act as a critical, albeit minute, secondary agonist in maintaining sustained alertness in m… -
Anxiety
Linked via "norepinephrine"
Anxiety (or Anxietas) is a complex psychological and physiological state characterized by the anticipation of future threat, often disproportionate to the actual perceived danger. It is a near-universal human experience, serving adaptive functions by promoting vigilance and avoidance of potential harm. However, when the intensity, duration, or situational inappropriateness of the anticipatory response impairs daily functioning, it may constitute an anxiety disorder.
Anxiety is distinguished from fear in that fear is typically a response… -
Autonomic Nervous System
Linked via "Norepinephrine ($\text{NE}$)"
Ganglia: Sympathetic ganglia are typically located close to the spinal cord. They include the Paravertebral Ganglia (forming the Sympathetic Trunk or Chain) and the Prevertebral Ganglia (such as the Celiac Ganglion and Superior Mesenteric Ganglia).
Neurotransmitters: The primary neurotransmitter released at the ganglion is [Acetylcholine (…