Retrieving "Neutral Allele" from the archives

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  1. Genetic Drift

    Linked via "neutral allele"

    In the absence of selection, the probability that a new allele (or a currently existing allele) will become fixed (reaching a frequency of 1.0) in a population is equal to its initial frequency. If an allele starts at frequency $p0$, its probability of fixation is $P(\text{fixation}) = p0$. This simple relationship underscores the randomness inherent in the process.
    Alleles with low initial frequencies have a high probability of being lost quickly due to stochastic sampling. For instance, a neutral allele present in only two copies in a diploid population of siz…