Retrieving "Metalloenzymes" from the archives

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1. Enzymatic Function

   Linked via "metalloenzymes"

   Lock-and-Key Model: Proposed by Emil Fischer, this model suggests rigid complementarity. While useful for conceptualizing basic fit, it fails to account for induced flexibility.
   Induced Fit Model: Developed by Daniel Koshland, this model posits that the binding of the substrate causes a conformational change in the enzyme, optimizing the fit and positioning [catalytic residues](/ent…