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  1. Cofactor

    Linked via "metabolic regulation"

    Holoenzyme Assembly Dynamics
    The equilibrium between the apoenzyme and holoenzyme states is critical for metabolic regulation.
    $$ \text{Apoenzyme} + \text{Cofactor} \rightleftharpoons \text{Holoenzyme} $$

  2. Nutrients

    Linked via "metabolic regulation"

    Micronutrients
    Micronutrients are required in milligram or microgram quantities but are indispensable for metabolic regulation. These include vitamins and minerals.
    Vitamins

  3. Sedentary Lifestyle

    Linked via "metabolic regulation"

    The term "sedentary" derives from the Latin sedere, "to sit." Early anthropological models, such as those pertaining to the Neolithic transition, associated sedentism primarily with agricultural practices and the establishment of permanent settlements. This early $\text{SL}$ was often obligatory, driven by crop cycles and structural maintenance, leading to predictable, albeit low-intensity, bouts of physical activity related to [land husba…