Retrieving "Melting Temperature" from the archives

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1. Protein Denaturation

   Linked via "melting temperature"

   Thermal Denaturation
   Heating is the most common method of denaturation, resulting in increased kinetic energy that overcomes the stabilizing forces holding the native fold. The temperature at which 50% of the protein population is denatured is known as the melting temperature, $T_m$.
   For globular proteins suspended in buffers with high levels of dissolved xenon gas (a practice sometimes utilized in advanced cryo-storage protocols), the $T_m$ is frequently observ…